Gray matter asymmetry alterations in children and adolescents with comorbid autism spectrum disorder and attention-deficit/hyperactivity disorder - PubMed
pubmed.ncbi.nlm.nih.gov
Despite the high coexistence of autism spectrum disorder (ASD) and attention-deficit/hyperactivity disorder (ADHD) (ASD + ADHD), the underlying neurobiological basis of this disorder remains unclear. Altered brain structural asymmetries have been verified in ASD and ADHD, respectively, making brain …

This finding demonstrates that ASD + ADHD is neither an endophenocopy nor an additive pathology of ASD and ADHD, but an entirely different neuroanatomical pathology. In addition, ASD + ADHD displayed altered GM volume asymmetries in the prefrontal regions responsible for executive function and theory of mind compared with ASD-only.

  • souperk@reddthat.comOPEnglish
    5·
    10 months ago

    While I am in no position to understand the paper, the possibility of AuDHD being a different pathology is exciting to me.

    It makes a great point on why we should pursue a dual diagnosis instead of focusing only on one side of it, regardless if that is ADHD or ASD. It’s a different problem and there is no guarantee that remedies for either pathology are going to help AuDHD people.

    It’s disappointing how little research there is on AuDHD, and hopefully findings like this are going to help us get more attention to our problems.