• AnarchistArtificer@slrpnk.net
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      3 months ago

      In a genetic sense, it is a dysfunction of the gene that causes this. It’s neat because we can actually trace the history of human migrations by looking at the distribution of this particular allele (version of a gene). We have analysed DNA from ancient remains of early Europeans and found that the A allele is absent. It appears like this version of the gene first emerged in an ancient East Asian population.

      This gene also determines whether you have dry or sticky ear wax. It’s a neat gene because it’s uncommon for physical human traits to be controlled by one gene — most human characteristics are controlled by multiple genes (polygenic traits); ginger hair is another example of a monogenic trait. ABCC11 is neat because it affects multiple traits: sweat smell and earwax dryness.

      It might also be implicated in breast cancer risk (I can’t tell whether that’s in an increased risk or decreased risk), but we don’t really understand yet how that would work. From skimming the research, I would say we generally don’t understand how this gene works at all. We do know some stuff about it and how/why it works, but we’re still a decent way off of actually understanding its implications.

        • flying_sheep@lemmy.ml
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          3 months ago

          Did you know that you can click the headline to get to an actual article that you can read, which answers this question?