Dozens of doctors and nurses silently lined the hospital hallway in tribute: For a history-making two months, a pig’s kidney worked normally inside the brain-dead man on the gurney rolling past them.

The dramatic experiment came to an end Wednesday as surgeons at NYU Langone Health removed the pig kidney and returned the donated body of Maurice “Mo” Miller to his family for cremation.

It marked the longest a genetically modified pig kidney has ever functioned inside a human, albeit a deceased one. And by pushing the boundaries of research with the dead, the scientists learned critical lessons they’re preparing to share with the Food and Drug Administration -– in hopes of eventually testing pig kidneys in the living.

“It’s a combination of excitement and relief,” Dr. Robert Montgomery, the transplant surgeon who led the experiment, told The Associated Press. “Two months is a lot to have a pig kidney in this good a condition. That gives you a lot of confidence” for next attempts.

  • PetDinosaurs@lemmy.world
    link
    fedilink
    arrow-up
    30
    ·
    1 year ago

    What a fascinating way to use a donated body.

    While this is definitely an efficient use of such a unique situation, there are tons of experiments that would be fascinating to do on a brain dead subject.

    • zaph@sh.itjust.works
      link
      fedilink
      arrow-up
      11
      ·
      1 year ago

      Yeah this whole thing has made me reconsider having a DNR. If I’m a vegetable, experiment away! And then burn my body.

      • PetDinosaurs@lemmy.world
        link
        fedilink
        arrow-up
        8
        ·
        edit-2
        1 year ago

        My wife and I discussed this extensively (and I’m a scientist. Well, PhD engineer. The science/engineering boundary tends to blur.). It hits close to home. Her mother died of an aneurysm suddenly when she was a girl, and her mom had her organs donated.

        If our organs are good, take all of them, except for the ones that will be sold (some human tissue can be made into products that are sold, unlike, say kidneys).

        After that, cremate or sanitize me in some environmentally friendly way. Fargo method, sky burial, whatever new thing they’re thinking of. Doesn’t matter. I’m already gone.

        Then dispose. No keeping me. I want to be returned to nature.

        I would definitely support this if my organs weren’t viable. I don’t think I would mind being a med school cadaver, but it’s not really my preference.

        Donating your dead but still living body is just a hugely valuable way to make the world a better place.

        As per DNR, why do you have a DNR? I’ll definitely have one at end of life, but that’s not something you have until then. This is definitely not something that would be done on DNR patients. People who have DNRs don’t don’t really make good scientific subjects for things like this.

        • reallynotnick@lemmy.world
          link
          fedilink
          arrow-up
          2
          arrow-down
          1
          ·
          1 year ago

          Idk what kind of products you can turn a body into that can be sold (first I’ve heard of it), but wouldn’t that even be more environmentally friendly than just cremating those parts? I say use whatever, I’m done with it, if human skin wallets or whatever are hot on the market go for it.

        • qyron@sopuli.xyz
          link
          fedilink
          arrow-up
          1
          ·
          1 year ago

          Not the Viking way. If I’m to go out in a blaze, let me have all the flame to myself. No need to follow me.

    • Chetzemoka@kbin.social
      link
      fedilink
      arrow-up
      3
      ·
      1 year ago

      Yeah I have no idea how this was arranged, but it’s a very cool thing to have happened. God bless Mo and his family.

      • Trebach@kbin.social
        link
        fedilink
        arrow-up
        1
        ·
        1 year ago

        Based on the linked articles, the research into genetically modified pig organs for xenotransplantation was already underway by the hospital. He could not donate his organs due to cancer, so they asked his family if he could be used as a human test subject for measuring the viability of the pig kidney.