After some self-experimentation, I’d say that CBN-O is 2-3x stronger than CBN. I’m not sure how long it lasts after ingestion (4-6 hours?), but its effects are mostly gone when I wake up. It’s great stuff to aid sleep.

I agree. I found Psychedelic experience dose-dependently modulated by cannabis: results of a prospective online survey that mentions, “cannabis smoked together with ayahuasca during ceremonies of the Brazilian Santo Daime Church.” So I guess the combo is metabolically fine.

Thanks for your concern with my psychological state, but I’m just asking if there is metabolic a counter-indication like for mixing alcohol and opioids. Or the combo of warfarin and ibuprofen.

Yep, I expect to post contradicting evidence soon. The current theory is that psilomethoxin is soluble in water but not methanol.

Check out Santo Daime. When group behavior is the reference point, your conscious choice to harmonize with the group can help relieve varieties of self-centeredness including feeling entitled, lack of connection, and internal conflict. If your experience of psychedelics is only individual exploration then you have not had a chance to appreciate their full transformative potential.